FIELD: medicine; pulmonology; medical genetics.
SUBSTANCE: invention can be used for predictive diagnosis of chronic obstructive pulmonary disease. If defects in axonemal dynein are detected, the function of the mucociliary system is examined. In the presence of a combination of generalized and severe mucociliary insufficiency, chronic obstructive pulmonary disease is diagnosed, and in the case of a combination of generalized and moderate mucociliary insufficiency, a predisposition to the development of this pathology is diagnosed.
EFFECT: method allows for predictive prevention and treatment of COPD due to the possibility of identifying a predisposition to this disease or diagnosing the disease at an early stage by assessing the totality of the most significant indicators.
1 cl, 2 ex
