FIELD: biotechnology; medicine.
SUBSTANCE: disclosed is an isolated isoform of Atlantic cod trypsin ZT containing the amino acid sequence SEQ ID NO: 2 or amino acid sequence with sequence homology of 99% or more, a medical composition based thereon and a method of treating diseases caused by picornaviruses, which involves administering a therapeutically effective amount of the composition.
EFFECT: new isoform of trypsin ZT is better adapted for cleavage of peptides containing several sequential basic amino acid residues Arg and Lys, has specific antiviral activity.
11 cl, 5 dwg, 4 tbl, 6 ex
Title | Year | Author | Number |
---|---|---|---|
NOVEL TRYPSIN ISOFORMS AND USE THEREOF | 2016 |
|
RU2739945C2 |
PORCINE TRYPSIN OPTIONS | 2019 |
|
RU2783315C2 |
CD40L ANTIBODIES AND METHODS OF TREATING CD40L RELATED DISEASES AND DISORDERS | 2016 |
|
RU2727646C2 |
IL2 AND MUTANT TNF IMMUNOCONJUGATES | 2017 |
|
RU2758139C2 |
AMATOXIN ANTIBODY-DRUG CONJUGATES AND USE THEREOF | 2020 |
|
RU2826004C2 |
FUSED PROTEIN CONSTRUCTS FOR COMPLEMENT-RELATED DISEASE | 2019 |
|
RU2824402C2 |
CHIMERIC ANTIGEN RECEPTORS TARGETED TO FC RECEPTOR-LIKE PROTEIN 5, AND THEIR USE | 2015 |
|
RU2779747C2 |
ANTICANCER VACCINES | 2017 |
|
RU2718663C2 |
METHOD FOR REDUCING ERRONEOUS INCLUSION OF NON-CANONICAL BRANCHED-CHAIN AMINO ACIDS | 2019 |
|
RU2816654C2 |
POLYVALENT AND POLYSPECIFIC GITR-BINDING FUSED PROTEINS | 2016 |
|
RU2753439C2 |
Authors
Dates
2024-03-04—Published
2016-07-22—Filed