NOVEL ISOFORM OF TRYPSIN AND USE THEREOF Russian patent published in 2024 - IPC C12N9/76 A61K38/48 A61K47/10 A61P11/00 A61P31/12 

Abstract RU 2814729 C2

FIELD: biotechnology; medicine.

SUBSTANCE: disclosed is an isolated isoform of Atlantic cod trypsin ZT containing the amino acid sequence SEQ ID NO: 2 or amino acid sequence with sequence homology of 99% or more, a medical composition based thereon and a method of treating diseases caused by picornaviruses, which involves administering a therapeutically effective amount of the composition.

EFFECT: new isoform of trypsin ZT is better adapted for cleavage of peptides containing several sequential basic amino acid residues Arg and Lys, has specific antiviral activity.

11 cl, 5 dwg, 4 tbl, 6 ex

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RU 2 814 729 C2

Authors

Gudmundsdottir, Agusta

Asgeirsson, Asgeir

Stefansson, Bjarki

Dates

2024-03-04Published

2016-07-22Filed