LIXISENATIDE AND METFORMIN FOR TYPE 2 DIABETES TREATMENT Russian patent published in 2017 - IPC A61K38/26 A61K31/64 A61K31/155 A61P3/10 

Abstract RU 2623023 C2

FIELD: pharmacology.

SUBSTANCE: pharmaceutical combination for patients with type 2 diabetes includes desPro36Exendin-4(1-39)-Lys6-NH2 and/or a pharmaceutically acceptable salt thereof, metformin and/or a pharmaceutically acceptable salt thereof and sulfonylurea. At that, the subject to be treated has postprandial plasma glucose concentration of at least 14 mmol/l 2 hours after ingestion. The group of inventions also relates to a method for plasma glucagon levels reduction in patients with type 2 diabetes comprising administration of the said combination.

EFFECT: reduced glucagon level in plasma.

22 cl, 11 dwg, 29 tbl, 2 ex

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RU 2 623 023 C2

Authors

Rus Peter

Silvestr Luiz

Moissek Patrik

Penke Zhan-Lui

Enselen-Meri Anes

Dates

2017-06-21Published

2012-05-11Filed