FIELD: biotechnology.
SUBSTANCE: present invention relates to biotechnology and can be used in medicine and diagnostics. Invention discloses an L-nucleic acid molecule containing a nucleotide sequence in a central fragment: 5’-GGAAGUACGUGGAAAGCCRA(Xu)RAGUGUGUCCCG-3’ [SEQ ID NO: 27], where Xu is U or is absent. L-nucleic acid according to the present invention is capable of specifically binding to human CXCL8 (IL-8), without interacting with other ELR-positive chemokines, and more preferably without binding with ELR-positive chemokines, which bind to receptors CXCR1 and/or CXCR2.
EFFECT: invention can be used as a diagnostic or drug for diagnosing or treating a disease characterized by the presence of CXCL8, which is directly or indirectly involved in the pathogenesis of the disease.
98 cl, 7 ex, 1 tbl, 9 dwg
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