FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, namely to cell technologies, and can be used in medicine for preparing drug for treating cancer. L-nucleic acid molecule is obtained, which binds to SDF-1, which contains in 5'→3' direction first section of nucleotides, core nucleotide sequence and second section of nucleotides or in 5'→3' direction second section of nucleotides, core nucleotide sequence and first section of nucleotides. Wherein core nucleotide sequence contains 5'GUGUGAUCUAGAUGUADWGGCUGWUCCUAGUYAGG3' (SEQ ID NO: 57), where said first and second sections of nucleotides have sufficient degree of reverse complementarity for hybridization with each other, where two-stranded structure is formed by hybridization and where two-stranded structure consists of four to six base pairs. Said nucleic acid can be modified with HES or PEG.
EFFECT: invention makes it possible to facilitate mobilization of cells expressing SDF-1 in patient's peripheral blood.
9 cl, 43 dwg, 3 tbl, 14 ex
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