Patenton — panteon of patents

(19)

RU

(11)

2 815 451

(13)

C2

(51)

IPC

C07K16/30(2006-01-01)

C07K16/28(2006-01-01)

C07K16/32(2006-01-01)

C07K14/52(2006-01-01)

A61K39/395(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2020135987, 2019-04-12

(24)

Start date

2019-04-12

(22)

Actual filing date

2019-04-12

(45)

Published

2024-03-15

(72)

Inventor

Ferrara Koller ClaudiaIuntilla Teemu TapaniKlein ChristianUmana PabloClaus Christiana

(73)

Holder

F. Hoffmann-La Roche Ag

HER-2-DIRECTED ANTIGEN-BINDING MOLECULES CONTAINING 4-1BBL Russian patent published in 2024 - IPC C07K16/30 C07K16/28 C07K16/32 C07K14/52 A61K39/395 A61P35/00 

Abstract RU 2815451 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to novel antigen-binding molecules. Invention discloses a HER2-specific antibody containing 4-1BBL-trimer.

EFFECT: invention can be used in medicine for treating cancer, including in combination with T-cell activating CD3-bispecific antibodies.

16 cl, 5 ex, 13 tbl, 16 dwg

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RU 2 815 451 C2

Authors

Ferrara Koller Claudia

Iuntilla Teemu Tapani

Klein Christian

Umana Pablo

Claus Christiana

Dates

2024-03-15—Published

2019-04-12—Filed

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