SUBSTITUTED HETEROCYCLIC FUSED CYCLIC COMPOUND, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL USE THEREOF Russian patent published in 2024 - IPC C07D403/04 C07D471/00 A61K31/495 A61P35/00 

Abstract RU 2815814 C1

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention relates to compounds of formula (IB) or their pharmaceutically acceptable salts, a pharmaceutical composition and use thereof in preparing medicinal agents.

EFFECT: novel compounds having a selective inhibitory effect on KRAS gene mutation, which can be used in preparing anticancer drugs, are obtained.

22 cl, 350 ex, 9 tbl, 2 dwg

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RU 2 815 814 C1

Authors

Zhou, Fusheng

Jiang, Tao

Lin, Chonglan

Cai, Lijian

He, Wan

Lan, Jiong

Dates

2024-03-21Published

2020-10-28Filed