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(19)

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2 817 609

(13)

(51)

IPC

C07H19/67(2006-01-01)

C07D405/04(2006-01-01)

A61K31/506(2006-01-01)

A61K31/7068(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2023126719, 2023-10-18

(24)

Start date

2023-10-18

(22)

Actual filing date

2023-10-18

(45)

Published

2024-04-16

(72)

Inventor

Shastina Natalia SergeevnaSiniavin Andrei EduardovichLuiksaar Sergei IgorevichZolotov Sergei AnatolevichSheremet Anna BorisovnaRemizov Timofei AndreevichZakharova Anastasiia AndreevnaVasina Daria VladimirovnaKleimenov Denis AleksandrovichPochtovyi Andrei AndreevichKuznetsova Nadezhda AnatolevnaUsachev Evgenii ValerevichIvanov Igor AndreevichRussu Leonid IvanovichShidlovskaya Elena VladimirovnaDarnotuk Elizaveta SergeevnaInshakova Anna MikhajlovnaSoloveva Anna VladimirovnaBondareva Nataliya EvgenevnaTerekhov Aleksandr AleksandrovichTokarskaya Elizaveta AleksandrovnaLubenets Nadezhda LeonidovnaLogunov Denis YurevichZigangirova Nailya AkhatovnaGushchin Vladimir AlekseevichGintsburg Aleksandr Leonidovich

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Uchrezhdenie Issledovatelskii Tsentr Epidemiologii I Mikrobiologii Imeni Pochetnogo Akademika N.F. Gamalei" Ministerstva Zdravookhraneniia Rossiiskoi Federatsii

5'-O-(4-CHLOROPHENOXYACETYL)-N4-HYDROXYCYTIDINE AND USE THEREOF Russian patent published in 2024 - IPC C07H19/67 C07D405/04 A61K31/506 A61K31/7068 A61P31/12

Abstract RU 2817609 C1

FIELD: pharmaceutics.

SUBSTANCE: group of inventions relates to a novel derivative of 5'-O-(4-chlorophenoxyacetyl)-N4-hydroxycytidine, as well as to a method for production thereof and use of the compound for inhibiting replication of SARS-CoV-2 coronavirus.

EFFECT: novel compound having high activity against coronavirus SARS-CoV-2 is obtained.

6 cl, 3 ex, 3 dwg

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RU 2 817 609 C1

Authors

Shastina Natalia Sergeevna

Siniavin Andrei Eduardovich

Luiksaar Sergei Igorevich

Zolotov Sergei Anatolevich

Sheremet Anna Borisovna

Remizov Timofei Andreevich

Zakharova Anastasiia Andreevna

Vasina Daria Vladimirovna

Kleimenov Denis Aleksandrovich

Pochtovyi Andrei Andreevich

Kuznetsova Nadezhda Anatolevna

Usachev Evgenii Valerevich

Ivanov Igor Andreevich

Russu Leonid Ivanovich

Shidlovskaya Elena Vladimirovna

Darnotuk Elizaveta Sergeevna

Inshakova Anna Mikhajlovna

Soloveva Anna Vladimirovna

Bondareva Nataliya Evgenevna

Terekhov Aleksandr Aleksandrovich

Tokarskaya Elizaveta Aleksandrovna

Lubenets Nadezhda Leonidovna

Logunov Denis Yurevich

Zigangirova Nailya Akhatovna

Gushchin Vladimir Alekseevich

Gintsburg Aleksandr Leonidovich

Dates

2024-04-16—Published

2023-10-18—Filed