ANTIBODY-DRUG CONJUGATES CONTAINING HERBOXYDIENE-BASED SPLICING MODULATOR, AND METHODS OF USE THEREOF Russian patent published in 2024 - IPC C07K17/02 A61K47/68 A61P35/00 

Abstract RU 2820607 C2

FIELD: biotechnology.

SUBSTANCE: described is a group of inventions comprising a splicing modulator or a pharmaceutically acceptable salt thereof, a compound for treating a neoplastic disorder, conjugate of an antibody and a drug for treating a neoplastic disorder, a pharmaceutical composition for treating a neoplastic disorder, use of a splicing modulator or a pharmaceutically acceptable salt thereof, a compound or a conjugate of an antibody and a drug for treating a neoplastic disorder, use of a splicing modulator or a pharmaceutically acceptable salt thereof, a compound or a conjugate of an antibody and a drug for preparing a drug for treating a neoplastic disorder and a method of treating a subject having a neoplastic disorder or suspected presence thereof.

EFFECT: invention extends the range of splicing modulation means.

27 cl, 6 dwg, 14 tbl, 4 ex

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RU 2 820 607 C2

Authors

Fishkin, Nathan

Samarakoon, Thiwanka

Palacino, James

Arai, Kenzo

Kotake, Yoshihiko

Okubo, Shinya

Murai, Norio

Miyano, Masayuki

Dates

2024-06-06Published

2019-12-12Filed