FIELD: medicine; pharmaceutics.
SUBSTANCE: present invention relates to the use of a caspase inhibitor for the manufacture of a medicament for the relief or treatment of osteoarthritis, having a long-lasting effect in a single administration, where the caspase inhibitor is selected from the group consisting of nivocasan and a pharmaceutically acceptable salt thereof.
EFFECT: present invention provides effective relief or treatment of osteoarthritis without causing a risk of side effects and demonstrating the effect of improving the function and structure of the cartilage, and also provides an analgesic effect for a long period of time only with a single introduction, without resistance to action.
17 cl, 7 dwg, 8 tbl, 6 ex
| Title |
Year |
Author |
Number |
| SCHEME FOR USING FGF-18 COMPOUND |
2015 |
- Ladel, Christoph H.
- Guehring, Hans
|
RU2700582C2 |
| SCHEME FOR USING FGF-18 COMPOUND |
2015 |
- Ladel, Christoph H.
- Guehring, Hans
|
RU2691946C2 |
| [(S)-1-CARBAMOYL-2-(PHENYLPYRIMIDIN-2-YLAMINO)ETHYL]AMIDE 2-(2-METHYLAMINOPYRIMIDIN-4-YL)-1H-INDOLE-5-CARBOXYLIC ACID FOR USE IN TREATING OSTEOARTHRITIS-RELATED PAIN |
2015 |
- Paehler, Tobias
- Flechsenhar, Klaus
- Grothe, Kirsten
- Lunnon, Martin
- Jan, Christelle
|
RU2687094C2 |
| METHODS TO REDUCE COMPLICATIONS FROM INTRA-ARTICULAR STEROID |
2019 |
- Shih, Sheue-Fang
- Chang, Po-Chun
- Wu, Ming-Ju
|
RU2806023C2 |
| THERAPEUTIC OR PREVENTIVE DRUG FOR TREATING OSTEOARTHRITIS |
2009 |
- Nishioka Kuzuki
- Judo Kazio
|
RU2492871C2 |
| APPLICATION OF K-252A DERIVATIVES TO TREAT DISORDERS OF PERIPHERAL OR CENTRAL NERVOUS SYSTEMS AND EXCESSIVE CYTOKINE OUTPUT |
1997 |
- Ehngber Tomas M.
- Khaun Forrest A.
- Saporito Majkl S.
- Ehjmon Lajza D.
- Miller Mehtt'Ju S.
- Najt Ehrnest Ml.
|
RU2183959C2 |
| TREATING OSTEOARTHRITIS AND PAIN |
2012 |
|
RU2563830C2 |
| METHOD FOR APPLYING ANNEALED PYRROLE COMPOUNDS WHEN TREATING ARTICULAR CARTILAGE DEGENERATION OR STRUCTURAL SUBCHONDRAL BONE TRANSFORMATIONS |
2002 |
- Pellet'E Zhan-P'Er
- Martel'-Pellet'E Zhoann
|
RU2303447C2 |
| OSTEOARTHRITIS TREATMENT COMPOSITION COMPRISING HYDROPHILISED SULPHASALASINE AND HYALURONIC ACID, AND A METHOD OF PRODUCING SAID COMPOSITION |
2016 |
- Kim Sukhvan
- Min Ken U
- Bek En Dzhun
- Li Son Khi
- Vu Ku
- Kim Min-Ken
|
RU2712168C1 |
| COMBINATION FOR TREATING OSTEOARTHRITIS |
2010 |
- Konti Franko
- Diogvardi Franchesko Saverio
|
RU2560844C2 |
