FIELD: biotechnology.
SUBSTANCE: invention relates to a chimeric antigen receptor which specifically binds to DLL3, a recovered polynucleotide coding it, as well as a vector and a cell containing said polynucleotide. Also disclosed is a composition and a bottle containing said cell. Invention also relates to a binding agent against DLL3, as well as to a composition containing same.
EFFECT: invention is effective for treating or preventing a condition associated with undesirable and/or elevated levels of DLL3.
59 cl, 16 dwg, 10 tbl, 16 ex
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