FIELD: chemistry.
SUBSTANCE: invention relates to a novel type of pyridine compounds, specifically to a compound of formula (1) or a pharmaceutically acceptable salt thereof, where R1 is aryl, heteroaryl, 
or 
, where aryl and heteroaryl are optionally substituted with 1–3 groups selected from the group consisting of halogen, C1-C3 alkyl, C1-C3 alkoxy, halogen-substituted C1-C3 alkyl or halogen-substituted C1-C3 alkoxy; R2 is H or methyl; R3 is H or F; W is 
and Ra is H, C1-C3 alkyl or C3-C6 cycloalkyl; and L is CH2, CO, CD2, CH(Me), C(Me)2, 
or 
.
EFFECT: development of new aurora kinase inhibitors with improved activity in vitro and in vivo.
5 cl, 4 tbl, 28 ex
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