FIELD: medicine; oncology.
SUBSTANCE: method of treating a disease caused by the kinase activity of c-KIT, its oncogenic forms or polymorphs, where the disease is a stromal tumor of the gastrointestinal tract, including the administration of a therapeutically effective amount of a dihydronaphthyridine derivative are proposed.
EFFECT: effectiveness against a wide range of primary and secondary c-KIT mutations with high therapeutic value for the treatment of patients with resistant GIST.
12 cl, 4 tbl, 184 ex
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