FIELD: biotechnology.
SUBSTANCE: disclosed is a bacterium from the genus Escherichia, which produces heparosan and has a genetic modification that increases expression of the kpsS gene compared to expression for an unmodified bacterium and does not have a genetic modification increasing expression of the kpsC gene compared to expression for an unmodified bacterium. Also disclosed is a method of producing heparosan using said bacteria.
EFFECT: invention provides effective production of heparosan.
11 cl, 3 dwg, 3 tbl, 6 ex
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