HEAVY CHAIN-ONLY ANTIBODIES THAT BIND TO CD19 Russian patent published in 2024 - IPC C07K16/28 A61K39/395 A61P35/00 

Abstract RU 2824170 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to an antibody containing only heavy chains, which binds to CD19. Also disclosed is a multispecific antibody which binds to CD19 and has binding affinity to CD3, a pharmaceutical composition containing said antibodies, method of treating diseases and conditions characterized by CD19 expression, including a B-cell disorder, use of said antibodies for treating a B-cell disorder and a kit for treating a disease or disorder characterized by CD19 expression.

EFFECT: invention provides antibodies containing only heavy chains, with binding affinity to CD19.

24 cl, 9 dwg, 1 tbl, 8 ex

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RU 2 824 170 C2

Authors

Aldred, Shelley Force

Van Schooten, Wim

Harris, Katherine

Rangaswamy, Udaya

Trinklein, Nathan

Dates

2024-08-07Published

2019-07-19Filed