FIELD: biotechnology.
SUBSTANCE: invention relates to a method of administering to a subject a therapeutically effective amount of a peptide or protein of up to 100 kilodaltons in an oral pharmaceutical composition which contains an isolated recombinantly expressed Bowman-Birk inhibitor (BBI), wherein said recombinantly expressed BBI is expressed in a yeast expression system, and said yeast expression system is Pichia pastoris.
EFFECT: invention provides improved long-term activity of therapeutic proteins and peptides.
15 cl, 6 dwg, 3 tbl, 4 ex
