FIELD: chemistry.
SUBSTANCE: invention relates to biochemistry, in particular to an isolated antibody or an antibody fragment which specifically binds to human PVRIG. Also disclosed is a nucleic acid coding said antibody; expression vector containing said nucleic acid; host cell containing said vector. Disclosed is a method of inhibiting PVRIG protein activity in a sample in vitro using said antibody.
EFFECT: invention has the ability to effectively inhibit PVRIG.
7 cl, 19 dwg, 2 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| NUCLEIC ACIDS ENCODING ANTIBODIES AGAINST SIALYLATED HUMAN LEWIS ANTIGEN | 2014 |
|
RU2791967C2 |
| MYL9 ANTIBODY | 2017 |
|
RU2741802C2 |
| TIGIT ANTIBODIES AND USE THEREOF | 2020 |
|
RU2827445C2 |
| NUCLEIC ACIDS ENCODING HUMAN ANTIBODIES TO SIALYL-LEWIS | 2014 |
|
RU2699289C2 |
| ANTIBODY AGAINST LAG-3, ITS ANTIGEN-BINDING FRAGMENT AND THEIR PHARMACEUTICAL APPLICATION | 2017 |
|
RU2757813C2 |
| ANTIBODIES AGAINST VISTA AND APPLICATION THEREOF | 2018 |
|
RU2750723C1 |
| HUMANIZED ANTIBODIES AGAINST BASIGIN AND THEIR APPLICATION | 2017 |
|
RU2755150C2 |
| ANTI-PD-1 ANTIBODY AND USE THEREOF | 2017 |
|
RU2739610C1 |
| NEW MONOCLONAL ANTIBODIES TO PROGRAMMED CELL DEATH 1 (PD-1) PROTEIN | 2016 |
|
RU2757316C2 |
| ANTIBODIES TO HUMAN INTERLEUKIN-2 AND THEIR APPLICATION | 2018 |
|
RU2745451C1 |
