FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, in particular to a bispecific antibody specifically binding human CEACAM5 and CD3ε person. Said antibody comprises a binding fragment specifically binding human CEACAM5 and a second binding fragment specifically binding CD3ε person. Present invention also relates to the use of said antibody for treating solid tumours expressing CEA in vivo, a pharmaceutical composition containing it, a polynucleotide, a vector and a cell for producing said antibody.
EFFECT: invention provides obtaining novel effective bispecific anti-CEAxCD3.
14 cl, 18 dwg, 7 tbl, 13 ex
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