FIELD: biotechnology.
SUBSTANCE: invention relates to a combination of antibodies for inducing immune tolerance to a cell obtained from an individual, containing an anti-CD86 antibody and an anti-CD80 antibody. Also disclosed is a nucleic acid molecule coding an anti-CD80 antibody or a variant thereof, a nucleic acid molecule coding an anti-CD86 antibody or a variant thereof, as well as a vector and a cell containing them. Invention also relates to a method of producing a cell involving the use of said combination.
EFFECT: invention is effective for induction of immune tolerance to a cell obtained in an individual.
9 cl, 9 dwg, 1 tbl, 6 ex
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Authors
Dates
2024-04-02—Published
2019-06-21—Filed