IMMUNE TOLERANCE INDUCING ANTIBODIES, INDUCED LYMPHOCYTES AND THERAPEUTIC AGENT/METHOD OF CELL THERAPY USING INDUCED LYMPHOCYTES Russian patent published in 2024 - IPC C07K16/28 A61K39/395 C12N5/783 C12N5/10 C12N15/13 C12N15/63 C12P21/08 A61P37/06 

Abstract RU 2816592 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to a combination of antibodies for inducing immune tolerance to a cell obtained from an individual, containing an anti-CD86 antibody and an anti-CD80 antibody. Also disclosed is a nucleic acid molecule coding an anti-CD80 antibody or a variant thereof, a nucleic acid molecule coding an anti-CD86 antibody or a variant thereof, as well as a vector and a cell containing them. Invention also relates to a method of producing a cell involving the use of said combination.

EFFECT: invention is effective for induction of immune tolerance to a cell obtained in an individual.

9 cl, 9 dwg, 1 tbl, 6 ex

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RU 2 816 592 C2

Authors

Maeda Ryu

Kawakami Masayuki

Uchida Koichiro

Takeda Kazuyoshi

Okumura Ko

Dates

2024-04-02Published

2019-06-21Filed