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2 827 432

(13)

(51)

IPC

A61K31/7068(2006-01-01)

A61K31/7072(2006-01-01)

A61K48/00(2006-01-01)

A61P43/00(2006-01-01)

(21) (22)

Application

2020112901, 2016-06-17

(24)

Start date

2016-06-17

(22)

Actual filing date

2016-06-17

(45)

Published

2024-09-26

(72)

Inventor

Khirano MichioGarone KaterinaMarti Ramon

(73)

Holder

Ze Trastis Of Kolambiya Yuniversiti In Ze Siti Of Nyu-JorkFundasio Ospital Universitari Val D'Ebron-Institut De Reserka

DEOXYNUCLEOSIDE THERAPY OF DISEASES CAUSED BY UNBALANCED NUCLEOTIDE POOLS, INCLUDING MITOCHONDRIAL DNA DEPLETION SYNDROMES Russian patent published in 2024 - IPC A61K31/7068 A61K31/7072 A61K48/00 A61P43/00

Abstract RU 2827432 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to pharmacological therapy, and can be used for treating mitochondrial DNA depletion syndrome (MDS), characterized by at least one mutation in the DGUOK gene. Therapeutically effective amount of a composition containing at least deoxyadenosine (dA) and deoxyguanosine (dG) is administered to a patient for this purpose.

EFFECT: method provides the effective treatment of MDS characterized by at least one mutation in the DGUOK gene by administering a composition containing dA and dG.

7 cl, 7 dwg, 5 ex

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RU 2 827 432 C2

Authors

Khirano Michio

Garone Katerina

Marti Ramon

Dates

2024-09-26—Published

2016-06-17—Filed