FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, namely to an isolated antibody or antigen-binding fragment against natriuretic peptide receptor-1 (NPR1), as well as to a composition containing same. Also disclosed is an isolated nucleic acid encoding an amino acid sequence of said antibody or a fragment thereof, as well as a vector and a cell containing said nucleic acid.
EFFECT: invention is effective for treating a renal disorder in a patient, as well as for treating a cardiovascular disorder in the patient.
22 cl, 31 dwg, 27 tbl, 21 ex
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