FIELD: chemistry.
SUBSTANCE: group of inventions relates to organic chemistry and includes rapamycin derivatives of formulas (I-X), (I), individual compounds specified in the claim, a based pharmaceutical composition, a method of treating and using them. In formulas (I-X), (I) values of radicals are as specified in the claim.
EFFECT: rapamycin derivatives having mTOR inhibitory activity.
40 cl, 48 tbl, 201 ex
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