CHEMOKINE RECEPTOR MODULATORS AND USE THEREOF Russian patent published in 2022 - IPC C07D487/04 A61K31/5377 A61P43/00 A61P37/02 A61P35/00 A61P29/00 

FIELD: pharmaceutics.

SUBSTANCE: invention relates to a compound of formula II or a pharmaceutically acceptable salt thereof, wherein X², X³, z₄, L⁷, R¹, R², R^3.2, R^3.3, R⁴, R⁷ are defined in the claims, as well as to a pharmaceutical composition containing said compound, which inhibits type 4 (CCR4) chemokine receptor.

EFFECT: compounds are intended for treating a disease or disorder mediated by CCR4, selected from an immunopathological disease or disorder, an inflammatory disease or disorder, a cardiovascular disease or disorder, a metabolic disease or disorder, or cancer.

27 cl, 2 tbl, 116 ex