USE OF HPK1 KINASE INHIBITOR IN PREVENTION AND/OR TREATMENT OF PATHOGENIC INFECTIONS IN ANIMALS Russian patent published in 2024 - IPC A61K31/4427 C07D417/14 C07D241/20 C07D409/04 C07D417/04 C07D401/14 C07D401/04 A61P31/14 

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention relates to medicine and pharmaceutics and discloses the use of an HPK1 kinase inhibitor, which is a small molecule inhibitor of general formula (V) or a pharmaceutically acceptable salt thereof, for preparing a drug for preventing and/or treating a disease or condition caused by or associated with a pathogenic infection in an animal; where the pathogen is a coronavirus. In general formula (V), R₁₀ is -H; R₁₁ is -N heterocyclic alkyl containing one monocyclic ring and 5–7 ring atoms, where H on heteroatom can be substituted with direct alkyl C_1-3; R₁ is -NH₂; R₄ and R₅ are -H; R₆₁, R₆₂, R₆₃, R₆₄ and R₆₅ are -H; R₆₂ is C≡C-R₇; R₇ is , where R₈ and R₉ are -CH₃.

EFFECT: use of the invention enables the effective treatment of diseases caused by coronaviruses in animals.

9 cl, 2 dwg, 2 tbl