VACCINES, STABLE AT ROOM TEMPERATURE Russian patent published in 2021 - IPC A61K35/76 A61K47/06 A61K9/14 A61P31/12 

FIELD: medicine; veterinary.

SUBSTANCE: group of inventions can be used to produce a vaccine containing a live attenuated canine virus. For this purpose, the dry vaccine composition contains non-reducing oligosaccharides in amount of 30 % to 80 % (wt/wt), amino acid stabilizer from 5 % to 40 % (wt/wt), protein stabilizer from 2 % to 20 % (wt/wt), filler-stabilizer in amount of 2 % to 25 % (wt/wt). Amino acid stabilizer is arginine, the live attenuated virus is a live attenuated canine virus selected from a group, consisting of carnivore plague virus, adenovirus, parainfluenza virus and any combination thereof. Said dry composition is obtained in form of a flat cake, obtained on membrane or filter, dried in powder form by sublimation drying in beads, by spray drying or by spray drying with freezing. Group of inventions also relates to a method for preparing said vaccine.

EFFECT: use of this group of inventions enables using a given composition of the vaccine to obtain a dry composition of vaccines containing CDV, CAV2, CPV and CPI, stable at room temperature, as well as given composition can be used for viral vaccines, obtained by drying in form of flat cakes in bottles.

22 cl, 16 tbl