METHOD OF TREATING PATIENTS WITH SEVERE PSEUDOMEMBRANOUS COLITIS Russian patent published in 2024 - IPC A61B17/00 A61M25/01 A61K31/04 A61K31/436 A61K31/198 A61K31/4704 A61K9/08 A61P1/04 A61P31/04 

FIELD: medicine; coloproctology.

SUBSTANCE: invention can be used in treating patients with severe pseudomembranous colitis. Prognostic scale ATLAS is used to assess the ineffectiveness of the drug therapy, and if score is 4–6 points, a therapeutic suspended ileostomy is formed. Catheter for administering drug solutions is delivered through the discharge loop of the ileostomy into the lumen of the colon. 125–250 g of Vancomycin, 500–1,000 mg of Metronidazole, 200–220 mg of Fidaxomicin in 500 ml of normal saline 2 times day for 10 days, 100–120 mg of Rebamipide in 500 ml of normal saline 2 times day for 10 days. Time between introduction of the first and second solutions is 6 hours.

EFFECT: method provides higher clinical effectiveness in the patients with severe pseudomembranous colitis, prevents recurrent clostridial infection by modifying the ileostomy and expanding the capabilities of the drug therapy.

1 cl, 3 ex