FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to clinical and laboratory diagnostics, and can be used to diagnose severe pseudomembranous colitis in patients who have had a coronavirus infection. The concentration of zonulin and alpha-1 antitrypsin in the feces of patients is determined and a hydrogen breath test is performed. At a concentration of zonulin of 400-500 ng/ml, a concentration of alpha-1 antitrypsin of 310-450 mcg/g and a hydrogen breath test at a hydrogen concentration of up to 42-88 ppm and a methane concentration of 27-67 ppm, severe pseudomembranous colitis is diagnosed in patients who have undergone coronavirus infection.
EFFECT: method provides an opportunity to increase the efficiency of early diagnosis of severe pseudomembranous colitis in patients who have had a coronavirus infection by determining the concentration of zonulin and alpha-1 antitrypsin in the feces of patients and performing a hydrogen breath test.
1 cl, 3 ex
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Authors
Dates
2022-12-26—Published
2022-05-06—Filed