METHODS OF TREATING CHOLESTASIS Russian patent published in 2024 - IPC A61K31/4995 A61K31/554 A61P1/16 A61P17/04 

FIELD: medicine; pharmaceutics.

SUBSTANCE: group of inventions relates to pharmaceutical industry, namely to use of maralixibate chloride. Use of maralixibate chloride for the treatment of Alajil syndrome (ALGS) in a paediatric subject in need of such treatment, in amount of 400 to 800 mcg/kg/day, at which the subject experiences itching before the introduction of maralixibate chloride. Use of maralixibate chloride for the treatment of Alajil syndrome (ALGS) in a paediatric subject in need of such treatment in amount of 800 mcg/kg/day, in which the subject experiences itching prior to administration of maralixibate chloride. Use of maralixibate chloride for treating Alajil's syndrome (ALGS) in a paediatric subject in need of such treatment in amount of 400 mcg/kg/day, in which the subject experiences itching before the introduction of maralixibate chloride.

EFFECT: use of the group of inventions provides the treatment of Alajil syndrome, as well as reduced severity of itching.

12 cl, 36 dwg, 19 tbl, 4 ex