HYBRID COMPOUNDS BASED ON FURAN-2(3H)-ONE AND CHROMENE-4(4H)-THIONE, HAVING ANTIBACTERIAL ACTIVITY, AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2024 - IPC C07D311/22 A61K31/352 A61P31/04 

FIELD: chemistry.

SUBSTANCE: group of inventions relates to new biologically active compounds – hybrid systems based on furan-2(3H)-one and chromene-4(4H)-thione of formula

,

where R¹=H, R²=H (1), or R¹=Cl, R²=H (2), or R¹=CH₃, R²=H (3), or R¹=CH₃, R²=CH₃ (4), or R¹=OCH₃, R²=H (5), as well as a method of producing said compounds having antibacterial action, namely antibacterial activity on Escherichia coli K-12 cell culture, and is intended for use in medicine as an antibacterial agent.

EFFECT: obtaining hybrid compounds having high antibacterial action.

2 cl, 6 dwg, 1 tbl, 6 ex