FIELD: chemistry.
SUBSTANCE: invention relates to prop-2-yn-1-yl(2Z)-2-[(3β,4α,8α,11α,14β,16β)-16-(acetyloxy)-3-(butylamino)-11-hydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoate (1)
as well as to the use of the amine derivative of the propargyl ester of fusidic acid according to claim 1 as an agent with antimicrobial activity for controlling human and animal diseases caused by gram-positive bacteria Staphylococcus aureus (MRSA) and pathogenic fungal cultures of Cryptococcus neoformans.
EFFECT: obtaining a novel compound which has low toxicity at maximum test concentration and exhibits antibacterial activity on Staphylococcus aureus (MRSA) and fungicidal activity on Cryptococcus neoformans.
2 cl, 2 tbl, 2 ex
| Title |
Year |
Author |
Number |
| PROP-2-IN-1-IL-(2Z)-2-[(3-alpha, 4-alpha, 8-alpha, 11-alpha, 14-beta, 16-beta)-16-(ACETYLOXY)-3.11-DIHYDROXY-4,8,10,14-TETRAMETHYLGONANE-17-YLIDENE]-6-METHYLHEPT-5-ENOATE, PREPARATION METHOD AND ANTIMICROBIAL PROPERTIES |
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|
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2019 |
- Salimova Elena Viktorovna
- Tretyakova Elena Valerevna
- Parfenova Lyudmila Vyacheslavovna
|
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|
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2019 |
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|
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2018 |
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