FIELD: medicinal chemistry.
SUBSTANCE: invention relates to the field of medicinal chemistry, namely to (1-Benzyl-1H-1,2,3-triazol-4-yl)methyl (Z)-2-((3S,4S,8S,10S,11R,14S, 16S)-16-acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthrene-17-ylidene)-6-methylhept-5-enoate (1), which has antimicrobial activity.
EFFECT: invention also relates to the use of said compound as an agent with antimicrobial activity for combating human and animal diseases caused by Gram-positive Staphylococcus aureus (MRSA) bacteria and pathogenic fungal cultures of Cryptococcus neoformans.
2 cl, 2 tbl, 2 ex
| Title |
Year |
Author |
Number |
| USE OF MANNICH BASES BASED ON FUSIDIC ACID AS COMPOUNDS WITH ANTI-TUMOUR ACTIVITY |
2023 |
- Salimova Elena Viktorovna
- Parfenova Liudmila Viacheslavovna
- Ishmetova Diana Valievna
- Zainullina Liana Fanzilevna
- Vakhitova Iuliia Venerovna
|
RU2819293C1 |
| PROP-2-IN-1-IL-(2Z)-2-[(3-alpha, 4-alpha, 8-alpha, 11-alpha, 14-beta, 16-beta)-16-(ACETYLOXY)-3.11-DIHYDROXY-4,8,10,14-TETRAMETHYLGONANE-17-YLIDENE]-6-METHYLHEPT-5-ENOATE, PREPARATION METHOD AND ANTIMICROBIAL PROPERTIES |
2021 |
- Salimova Elena Viktorovna
- Savchenko Rimma Gafurovna
- Parfenova Lyudmila Vyacheslavovna
|
RU2780014C1 |
| (2Z)-2-[(3Β, 4Α, 8Α, 11Α, 14Β, 16Β)-16-(ACETYLOXY)-3-({3-[(4-AMINOBUTYL)AMINO]PROPYL}AMINO)-11-HYDROXY-4,8,10,14-TETRAMETHYL GONANE-17-YLIDENE]-6-METHYLHEPT-5-ENOIC ACID WITH ANTIMICROBIAL AND FUNGICIDAL ACTIVITY AND METHOD FOR PRODUCTION THEREOF |
2019 |
- Salimova Elena Viktorovna
- Tretyakova Elena Valerevna
- Parfenova Lyudmila Vyacheslavovna
|
RU2730604C1 |
| N,N'-BIS(3-AMINOPROPYL)BUTANE-1,4-DIAMINO DERIVATIVES OF FUSIDIC ACID, HAVING A WIDE SPECTRUM OF ANTIMICROBIAL ACTIVITY |
2019 |
- Salimova Elena Viktorovna
- Tretyakova Elena Valerevna
- Parfenova Lyudmila Vyacheslavovna
|
RU2726196C1 |
| (2Z)-2-[(4Α, 5Α, 8Α, 9Β, 13Α, 14Β, 16Β)-16-(ACETYLOXY)-3(Z),11(E)-BIS (HYDROXYIMINO)-4,8,10,14-TETRAMETHYLGONANE-17-YLIDENE]-6-METHYLHEPT-5-ENOIC ACID, METHOD OF PRODUCING AND ANTIMICROBIAL PROPERTIES |
2019 |
- Salimova Elena Viktorovna
- Tretyakova Elena Valerevna
- Parfenova Lyudmila Vyacheslavovna
|
RU2726122C1 |
| NEW NAPHTHO[2,1-B]CARBAZOL DERIVATIVES OF FUSIDIC ACID, METHOD OF SYNTHESIS AND ANTI-MICROBIAL PROPERTIES |
2019 |
- Salimova Elena Viktorovna
- Tretyakova Elena Valerevna
- Parfenova Lyudmila Vyacheslavovna
- Dzhemilev Usein Memetovich
|
RU2746947C2 |
| REGULATORS OF DERIVATIVES OF STEROIDS, METHODS OF THEIR OBTAINING AND USE |
2019 |
- Su Yidong
- Chen Xiaopo
- Wang Jun
- Bao Rudi
|
RU2803499C1 |
| REGULATORS-DERIVATIVES OF STEROIDS, METHODS OF THEIR OBTAINING AND THEIR USE |
2019 |
- Su Yidong
- Deng Haining
- Chen Xiaopo
- Bao Rudi
- Zhang Fujun
|
RU2797408C2 |
| NEW AMINE DERIVATIVES OF FUSIDIC ACID EXHIBITING ANTITUMOUR ACTIVITY |
2019 |
- Salimova Elena Viktorovna
- Tretyakova Elena Valerevna
- Parfenova Lyudmila Vyacheslavovna
|
RU2735665C1 |
| METHOD OF PRODUCING 1-(3-HYDROXY, 28-ACETOXY-LIP-20(29)-EN-30-YL)-PYRIDINIUM BROMIDE AND USE THEREOF AS AN AGENT WITH ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY |
2018 |
- Parfenova Lyudmila Vyacheslavovna
- Shakurova Elvira Rifovna
- Ponedelkina Irina Yurevna
|
RU2725873C2 |
