FIELD: biotechnology.
SUBSTANCE: group of inventions relates to biotechnology and can be used in medicine. Disclosed is a conjugate of an antibody targeting a tumour antigen with eribulin derivatives - cytotoxic agents acting on tubulin and preventing normal cell mitosis.
EFFECT: invention can be used in therapy of various malignant new growths.
56 cl, 7 ex, 11 tbl, 2 dwg
| Title |
Year |
Author |
Number |
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2020 |
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|
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| CONJUGATE OF TROP-2 ANTIBODY AND EXATECAN ANALOGUE AND MEDICAL USE THEREOF |
2021 |
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- Hu Qiyue
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|
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| ANTI-CLAUDIN 18.2 ANTIBODY AND USE THEREOF |
2020 |
- Yan, Yan
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|
RU2822550C2 |
| ANTIBODY TO CD3 AND ITS PHARMACEUTICAL USE |
2019 |
- Ying Hua
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|
RU2802272C2 |
| PHARMACEUTICAL COMPOSITION CONTAINING ANTIBODY TO SOST, AND ITS USE |
2018 |
- Fang Jingjing
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|
RU2779430C2 |
| ANTIBODY TO PD-1, ITS ANTIGEN-BINDING FRAGMENT AND ITS PHARMACEUTICAL USE |
2020 |
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|
RU2807484C2 |
| PHARMACEUTICAL COMPOSITION BASED ON ANTIBODIES AGAINST CD40 AND APPLICATION THEREOF |
2019 |
- Yang, Jianjian
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- Liu, Xun
- Jiang, Jiahua
|
RU2778572C1 |
| CONNECTIVE TISSUE GROWTH FACTOR ANTIBODY AND USE THEREOF |
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|
RU2819228C2 |
| PHARMACEUTICAL COMPOSITION BASED ON ANTIBODY TO PD-L1 AND ITS APPLICATION |
2018 |
- Yan, Zhen
- Yang, Jianjian
- Yan, Xiaodan
- Wu, Shan
- Liu, Xun
|
RU2766590C2 |
| PHARMACEUTICAL COMPOSITION CONTAINING ANTIBODY TO LAG-3 AND ITS USE |
2018 |
- Wu Tingting
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|
RU2771384C2 |
