FIELD: chemistry.
SUBSTANCE: invention relates to type I crystals of 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile showing characteristic peaks in X-ray powder diffractometry at diffraction angles 2θ of about 10.1°, 16.0°, 20.4°, 25.7° and 26.7°. The invention also relates to a method of obtaining type I crystals.
EFFECT: new crystals with higher solubility and higher thermal stability are obtained, compared to its hydrate and type II crystals.
2 cl, 8 dwg, 4 ex
| Title |
Year |
Author |
Number |
| PROCESS FOR PREPARATION OF 4-[5-(PYRIDIN-4-YL)-1H-1,2,4-TRIAZOL-3-YL]PYRIDINE-2-CARBONITRILE AND ITS INTERMEDIATE |
2013 |
- Ivabuti Josiyuki
- Miyata Satikho
- Uda Dzunitiro
- Nagata Osamu
|
RU2644766C2 |
| NOVEL CRYSTALLINE SALT FORM 3-(1,2,4-TRIAZOLO[4,3-A]PYRIDIN-3-YLETHYNYL)-4-METHYL-N-(4-((4-METHYLPIPERAZIN-1-YL)METHYL)-3-TRIFLUOROMETHYLPHENYL) BENZAMIDE FOR MEDICAL APPLICATION |
2016 |
- Chilov Germes Grigorevich
- Titov Ilya Yurevich
|
RU2652992C2 |
| CRYSTALLINE FORMS OF 1-((2R,4R)-2-(1H-BENZO[D]IMIDAZOL-2-YL)-1-METHYLPIPERIDIN-4-YL)-3-(4-CYANOPHENYL)UREA MALEATE |
2016 |
- Hansen, Eric Christian
- Seadeek, Christopher Scott
|
RU2717564C2 |
| CRYSTAL (6S,9AS)-N-BENZYL-8-({6-[3-(4-ETHYLPIPERAZIN-1-YL)AZETIDIN-1-YL]PYRIDIN-2-YL}METHYL)-6-(2-FLUORINE-4-HYDROXYBENZYL)-4,7-DIOXO-2-(PROP-2-EN-1-YL)HEXAHYDRO-2H-PYRAZINO[2,1-C][1,2,4]TRIAZINE-1(6H)-CARBOXAMIDE |
2016 |
|
RU2723551C2 |
| CRYSTAL FORM AND SALT 3-(3,5-DICHLORO-4-HYDROXYBENZOIL)- 1,1-DIOXO-2,3-DIHYDRO-1,3-BENZOTHIAZOLE |
2018 |
- Uda, Junichiro
- Kobashi, Seiichi
- Hasegawa, Misa
|
RU2772043C2 |
| CRYSTALLINE MODIFICATIONS OF 3-(1H-INDOL-3-YL)-4-(4-METHYLPIPERAZIN-1-YL)QUINAZOLIN-4-YL)PYRROL-2,5-DIONE |
2007 |
- Karpinski P'Otr
- Monn'E Stefani
- Ndz'E Ehl'Jas
- Papoutsakis Dimitris
- Satton Pol Allen
|
RU2481341C2 |
| POLYMORPH FORM OF 4-{[4-({[4-(2,2,2-TRIFLUOROETHOXY)-1,2-BENZISOXAZOL-3-YL]OXY}METHYL)PIPERIDIN-1-YL]METHYL}-TETRAHYDRO-2H-PYRAN-4-CARBOXYLIC ACID |
2012 |
- Numata Tojokharu
- Noguti Khirokhide
- Vaizumi Nobuaki
- Kodzima Takasi
|
RU2616978C2 |
| 7-{(3S,4S)-3-[(CYCLOPROPYLAMINO)METHYL]-4-FLUOROPYRROLIDIN-1-YL}-6-FLUORO-1-(2-FLUOROETHYL)-8-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID CRYSTAL |
2012 |
- Araya Itiro
- Goto Akinori
- Minagava Vataru
- Funada Keiko
- Nagao Muneki
|
RU2615509C2 |
| CRYSTALLINE FORM OF INHIBITOR BISULPHATE JAK AND METHOD FOR PRODUCTION THEREOF |
2015 |
- Sun Pyaoyan
- U Guajli
- Gao Syaokhuej
- Chen Yuntszyan
- Shen Lintszya
|
RU2704795C2 |
| METHOD FOR OBTAINING TRIAZOLOPYRIDINE COMPOUND |
2017 |
- Simoma, Fumito
- Yamaguti, Takasi
- Sagava, Soiti
|
RU2752384C2 |
