USE OF 3-AROYL-4-HYDROXY-1-(2-HYDROXYETHYL)-4'H-SPIRO[PYRROLE-2,5'-[1,2,5]OXADIAZOLO[3,4-b]PYRAZINE]-5,6'(1H,7'H)-DIONES AS AGENTS, HAVING ANTIMICROBIAL ACTIVITY AGAINST STAPHYLOCOCCUS AUREUS AND CANDIDA ALBICANS Russian patent published in 2024 - IPC A61K31/499 A61P31/04 A61P31/10 

Abstract RU 2831252 C1

FIELD: organic chemistry.

SUBSTANCE: invention relates to use of individual compounds of the class of spiro[pyrrole-oxadiazolopyrazines] of formulas 2c, 2d as agents having antimicrobial activity.

where Ar = 4-BrC6H4 (c), 4-MeC6H4 (d).

EFFECT: pronounced inhibitory action of compounds 2c, 2d on cultures of Staphylococcus aureus, Candida albicans.

1 cl, 1 tbl, 3 ex

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RU 2 831 252 C1

Authors

Tretiakov Nikita Alekseevich

Maslivets Andrei Nikolaevich

Balandina Svetlana Iurevna

Dates

2024-12-03Published

2024-03-27Filed