FIELD: biotechnology.
SUBSTANCE: present invention relates to molecular biology. Described is a double-stranded RNA-i molecule and a pharmaceutical composition containing said molecule. Said pharmaceutical composition is intended for use in prevention to prevent or reduce the frequency of bleeding episodes in a patient with haemophilia A or haemophilia B with or without inhibitors. Methods of preventing or reducing the frequency of bleeding episodes in these patients are also described.
EFFECT: wider range of products for treating and preventing haemophilia.
19 cl, 50 dwg, 22 tbl, 16 ex
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