FIELD: biotechnology.
SUBSTANCE: invention relates to an antibody which binds to CD3 and to TYRP-1, containing a first antigen-binding domain, which binds CD3 and a second and optionally a third antigen-binding domain, which binds TYRP-1, a method for production thereof, as well as a composition containing same. Also disclosed is an isolated polynucleotide coding said antibody, as well as a host cell containing said antibody.
EFFECT: invention is effective for treating cancer in an individual.
35 cl, 32 dwg, 7 tbl, 13 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIBODIES BINDING TO CD3 | 2019 |
|
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| POLYPEPTIDE LINKER FOR PRODUCTION OF MULTI-SPECIFIC ANTIBODIES | 2018 |
|
RU2776302C2 |
