FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, namely to a multi-domain binding molecule capable of binding a peptide-major histocompatibility complex (pMHC), which contains a pMHC binding fragment, which is associated with an immune effector that attracts T-cells, and a domain which increases half-life, containing an immunoglobulin Fc or an albumin binding domain, a composition containing the same, as well as a method for preparing the same. Also disclosed is an expression vector containing a nucleic acid coding said multi-domain binding molecule, as well as a cell containing said vector.
EFFECT: invention is effective for treating cancer or tumour.
14 cl, 4 dwg, 3 ex
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Authors
Dates
2025-01-23—Published
2020-01-30—Filed