FIELD: pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical industry, namely to a composition based on ciprofloxacin and 7-hydroxycoumarin. Disclosed is a composition based on ciprofloxacin and 7-hydroxycoumarin, which inhibits the quorum sensing system LuxI/LuxR-type in bacteria with the following ratio of components, when forming the composition, mcg/ml: ciprofloxacin – from 0.001 to 0.025, 7-hydroxycoumarin – from 5 to 129.
EFFECT: use of the invention enables to obtain a composition having a pronounced additive effect in inhibiting the quorum sensing system (QS) and an enhanced antibacterial effect, and also enables to reduce the amount of the antibiotic used.
1 cl, 3 dwg, 1 ex
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