FIELD: biotechnology.
SUBSTANCE: disclosed is a metabiotic composition for treating and/or preventing diseases associated with a disturbed composition of the microbiota of the gastrointestinal tract and/or intoxication of the body, including 0.1–7.0 wt.% of a complex of metabolites obtained from a culture fluid of at least one probiotic strain of Bacillus subtilis bacteria and/or bacteria of the Lactobacillaceae family and 93.0–99.9 wt.% aluminosilicate sorbent; and a method for production thereof, comprising growing at least one probiotic strain of bacteria Bacillus subtilis and/or bacteria of the Lactobacillaceae family in a liquid nutrient medium, centrifuging the culture suspension to obtain a culture liquid and a precipitate, ultrafiltration of the culture liquid. Obtained concentrate is dried and mixed with an aluminosilicate sorbent or dried on an aluminosilicate sorbent.
EFFECT: inventions provide a wider range of agents for treating and/or preventing diseases associated with intestinal dysbacteriosis and/or body intoxication.
22 cl, 1 dwg, 7 tbl, 9 ex
Title | Year | Author | Number |
---|---|---|---|
METABIOTIC COMPOSITION BASED ON METABOLITES OF BACILLUS SUBTILIS | 2022 |
|
RU2803259C1 |
METABIOTIC COMPOSITION TO ENSURE COLONISATION RESISTANCE OF HUMAN INTESTINAL MICROBIOCENOSIS | 2015 |
|
RU2589818C1 |
BACILLUS SUBTILIS SUBSP. INAQUOSORUM WITH ANTAGONISTIC ACTION AGAINST PATHOGENIC AND OPPORTUNITICAL MICROORGANISMS | 2022 |
|
RU2787384C1 |
SYNBIOTIC COMPOSITION FOR CORRECTION OF DYSBIOTIC GASTROINTESTINAL TRACT MICROBIOCENOSIS DISTURBANCES | 2015 |
|
RU2592988C1 |
COMPOSITION FOR CORRECTION OF DYSLIPIDEMIA AND MAINTENANCE OF FUNCTIONAL STATE OF HUMAN BODY IN METABOLIC SYNDROME | 2018 |
|
RU2681853C1 |
COMPOSITION WITH ANTI-INFECTIOUS ACTIVITY | 2012 |
|
RU2476205C1 |
BIOLOGICALLY ACTIVE FOOD ADDITIVE | 2013 |
|
RU2552006C1 |
MINERAL FEED ADDITIVE WITH PROBIOTIC ACTIVITY | 2014 |
|
RU2569002C1 |
METHOD OF PRODUCING FODDER COMPOSITION WITH FUNCTIONAL PROPERTIES FOR POULTRY FARMING | 2023 |
|
RU2819889C1 |
PREPARATION "BACSTITATIN" FOR TREATING DISEASES OF GASTROINTESTINAL TRACT | 2005 |
|
RU2287335C1 |
Authors
Dates
2025-01-31—Published
2023-07-31—Filed