FIELD: chemistry.
SUBSTANCE: present invention relates to pyrido[3,2-d]pyrimidine compounds, specifically to a compound selected from a group of individual compounds specified in the claim, and pharmaceutically acceptable salts thereof. Invention also relates to a pharmaceutical composition containing such a compound or a salt, to the use of such a compound, a salt and a composition, as well as a method of treating abnormal cell growth, including cancer.
EFFECT: disclosed compounds act as covalent inhibitors of HER2 and can be used to treat abnormal cell growth.
8 cl, 5 tbl, 456 ex
| Title | Year | Author | Number |
|---|---|---|---|
| INHIBITOR COMPOUNDS | 2013 |
|
RU2673079C2 |
| KINASE INHIBITORS | 2013 |
|
RU2637944C2 |
| GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION CONTAINING IT AND A METHOD OF ITS PREPARATION | 2021 |
|
RU2800290C1 |
| SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF | 2013 |
|
RU2607081C2 |
| DERIVATIVES OF HETEROARYLCARBAMOYLBENZENE | 2004 |
|
RU2330030C2 |
| CONDENSED 4-OXOPYRIMIDINE DERIVATIVE | 2005 |
|
RU2358969C2 |
| AMINOTRIAZOLOPYRIDINES AND USING THEM AS KINASE INHIBITORS | 2009 |
|
RU2552642C2 |
| TRIAZOLE[4,5-d]PYRIMIDINE DERIVATIVES AND USES THEREOF AS PUTINOCEPTOR ANTAGONISTS | 2002 |
|
RU2317084C2 |
| HETEROARYL DERIVATIVE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, A METHOD FOR PRODUCTION THEREOF AND A PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAID ACTIVE SUBSTANCE | 2016 |
|
RU2719367C2 |
| SUBSTITUTED PYRIDINE AND PYRAZINE COMPOUNDS AS PDE4 INHIBITORS | 2014 |
|
RU2802185C2 |
