TRIAZOLE[4,5-d]PYRIMIDINE DERIVATIVES AND USES THEREOF AS PUTINOCEPTOR ANTAGONISTS Russian patent published in 2008 - IPC A61K31/505 A61P25/28 C07D487/04 

FIELD: medicine, pharmaceuticals.

SUBSTANCE: invention relates to compound of general formula I having structure of triazole[4,5-d]pyrimidine derivatives, or pharmaceutically acceptable salts, or prodrugs thereof. Disclosed is method for application of said compound or pharmaceutically acceptable salt thereof to produce pharmaceutical for treatment and prophylaxis of conditions ameliorated with blockage of adenosine A_2A receptors. Also disclosed are pharmaceutical composition including compound of formula I, or pharmaceutically acceptable salt, or prodrug thereof in combination with pharmaceutically acceptable carrier or excipient. Said pharmaceutical compositions may be administered to subject by peroral, rectal, parantheral, transdermal, subdermal, etc. methods. Pharmaceutical of present invention are useful in treatment of Parkinson's disease, depression, cognitive or mental disturbances, acute or chronic pain, narcolepsy, etc.

EFFECT: composition of improved neuroprotective characteristics.

50 cl, 3 tbl