FIELD: chemistry.
SUBSTANCE: invention relates to chemistry, specifically to a method of producing a suspension of a biodegradable nanomaterial based on serum albumin, according to which the initial serum albumin is dissolved in water in a ratio of serum albumin to water of 1:5 to 1:1,000 by weight, then serum albumin is ionized with a buffer solution until pH 9.0 is achieved, an organic solvent selected from the following group is added to the obtained solution: ethyl alcohol, acetone, acetonitrile, in ratio of serum albumin solution in water : organic solvent, equal to from 1:2 to 1:10 by volume, then the obtained mixture is transferred into a container and exposed to ultraviolet radiation with wavelength of 253.7 nm with energy from 0.22 to 2.66 J/cm2 for 5-60 minutes, then the obtained suspension of serum albumin nanoparticles is subjected to three-fold centrifugation to remove residues of unbound serum albumin and transferring the finished suspension of serum albumin nanoparticles for storage in a corresponding organic solvent in ratio of 1:1,000 by volume.
EFFECT: high stability of the obtained suspension of biodegradable nanomaterial based on albumin and prolonged storage life.
3 cl, 5 dwg, 6 ex
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Authors
Dates
2025-04-08—Published
2024-05-30—Filed