FIELD: pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical industry, namely to a method for producing a dry extract of a higher plant Comarum salesovianum, having anti-influenza activity. Method for producing a dry extract of a higher plant Comarum salesovianum, having anti-influenza activity, comprising grinding raw material of Comarum salesovianum, obtaining an extract by remaceration, its subsequent filtration and removal of the solvent to obtain a dry extract exhibiting activity on the RNA genomic influenza virus of subtypes A/H3N2 and A/H5N1, at that, the raw material used is the roots of Comarum salesovianum plant, the extractant used is purified water, or 70% aqueous solution of ethanol, or ethyl acetate, or n-butanol in the ratio of dry material : extractant 1:40 with triple extraction in a boiling water bath for 30 minutes with successive reduction of the amount of extractant by 25% at the second and third extraction stages, combining the obtained extracts; filtration, distillation of extractants and drying to obtain extractive substances.
EFFECT: method described above enables to expand the range of agents with antiviral activity against human influenza A(H3N2) and avian A(H5N1) virus.
1 cl, 4 tbl, 9 ex
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Authors
Dates
2025-04-24—Published
2024-06-17—Filed