METHODS OF USING CYCLIC AMIDE DERIVATIVES FOR TREATING SIGMA RECEPTOR MEDIATED DISORDERS Russian patent published in 2025 - IPC A61K31/4035 A61K31/445 A61P25/18 

Abstract RU 2840025 C2

FIELD: medicine; pharmaceutics.

SUBSTANCE: group of inventions refers to pharmaceutical industry, namely to methods of treating schizoaffective disorder. Method of treating schizoaffective disorder, as well as a method of treating or relieving at least one symptom of schizoaffective disorder in a subject, in need thereof, comprising administering to a subject one to four times day from 1 mg to 64 mg of a compound of formula (II)

or a pharmaceutically acceptable salt, hydrate or solvate thereof. Method of treating schizoaffective disorder, as well as a method of treating or relieving at least one symptom of schizoaffective disorder in a subject, in need thereof, comprising administering to a subject twice day 32 mg of a compound of formula (II) or a pharmaceutically acceptable salt, hydrate or solvate thereof.

EFFECT: use of the group of inventions provides the treatment of schizoaffective disorder, namely the immediate improvement of negative symptoms, which lasts throughout the course of treatment, improvement of positive symptoms after four weeks of treatment, effective reduction of negative and positive symptoms for more than twelve weeks, as well as improved memory, anxiety and sleep with minimal side effects.

15 cl, 2 ex

Similar patents RU2840025C2

Title Year Author Number
METHODS FOR THE USE OF CYCLIC AMIDE DERIVATIVES FOR TREATMENT OF SIGMA-RECEPTOR-MEDIATED DISORDERS 2011
  • Luthringer, Remy, Henri
  • Pellegrini, Lorenzo
  • Karabelas, Argeris, N.
RU2746871C2
METHODS OF USING CYCLIC AMIDE DERIVATIVES FOR TREATING SIGMA-RECEPTOR MEDIATED DISORDERS 2011
RU2613201C2
METHODS FOR USING CYCLIC AMIDE DERIVATIVES FOR TREATING SCHIZOPHRENIA 2011
  • Lutringer Remi Anri
  • Pellegrini Lorentso
  • Karabelas Argeris N.
RU2576611C2
MIXTURE CONTAINING CARBAMATE COMPOUND FOR PREVENTION, RELIEF OR TREATMENT OF SCHIZOPHRENIA 2018
  • Joung, Chan Mi
  • Hwang, Sun Gwan
  • Lee, Ji Won
  • Jang, Young Koo
RU2772465C2
DERIVATIVES OF 7-FLUORO-8-CHLORO-5H-DIBENZO [B, E] [1, 4] DIAZEPINE AND THEIR APPLICATION 2014
  • Zapolskij Maksim Eduardovich
  • Morozova Margarita Alekseevna
  • Beniashvili Allan Gerovich
RU2610169C2
USING ROLUPERIDONE TO TREAT NEGATIVE SYMPTOMS AND DISEASES, INCREASE NEUROPLASTICITY AND PROMOTE NEUROPROTECTION 2019
  • Luthringer, Remy Henri
RU2812786C2
PHARMACEUTICAL COMPOSITIONS CONTAINING AN ANTIPSYCHOTIC DRUG AND A VMAT2 INHIBITOR, AND THEIR USE 2015
  • Khoar Semyuel Rodzher Dzhess
RU2757221C2
TREATING COGNITIVE DISORDERS WITH (R)-7-CHLOR-N-(QUINUCLIDIN-3-YL) BENZO[b] THIOPHEN-2-CARBOXAMIDE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS 2009
  • Kenig Gerkhard
  • Chesuort Richard
  • Shapiro Gideon
RU2532327C2
TREATMENT OF COGNITIVE DISORDERS WITH (R)-7-CHLORO-N-(QUINUCLIDIN-3-YL)BENZO[B]THIOPHENE-2-CARBOXAMIDE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF 2014
  • Kenig Gerkhard
  • Chesuort Richard
  • Shapiro Gideon
RU2662560C2
LIGAND WITH WIDE RANGE OF SIMULTANEOUS RECEPTOR ACTIVITY, PHARMACEUTICAL COMPOSITION, METHOD OF PREPARING SAID COMPOSITION AND MEDICINAL AGENT 2008
  • Ivashchenko Aleksandr Vasil'Evich
  • Ivashchenko Andrej Aleksandrovich
  • Savchuk Nikolaj Filippovich
RU2374245C1

RU 2 840 025 C2

Authors

Luthringer, Remy, Henri

Pellegrini, Lorenzo

Karabelas, Argeris, N.

Dates

2025-05-15Published

2021-04-09Filed