FIELD: medicine.
SUBSTANCE: group of inventions relates to the treatment of schizophrenia. A combination for the prevention, relief or treatment of schizophrenia includes (a) a carbamate compound of the following formula 1 or its pharmaceutically acceptable salt, solvate or hydrate; and (b) aripiprazole or its pharmaceutically acceptable salt, solvate or hydrate: [formula 1], in which each R1 and R2 is independently selected from a group consisting of hydrogen, halogen and C1-C8 alkyl; and one of A1 and A2 is CH, and the other is N. A pharmaceutical composition for the prevention, relief or treatment of schizophrenia is also disclosed.
EFFECT: group of inventions provides for improved effect without an increase in side effects.
17 cl, 1 dwg, 2 tbl, 2 ex
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Authors
Dates
2022-05-20—Published
2018-11-13—Filed