TWO-COMPONENT PREPARATION BASED ON SYNOVIAL FLUID AND METHOD FOR PREPARING TWO-COMPONENT PREPARATION BASED ON SYNOVIAL FLUID Russian patent published in 2025 - IPC A61K35/16 A61K35/17 A61P19/02 

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely to traumatology and orthopaedics, and can be used for preparing a two-component preparation of synovial fluid. Two-component preparation contains thrombocyte-enriched synovial fluid or normal saline. Preparation is obtained naturally, in volume of 25–40 ml, by sampling from the articulate cavity of a healthy joint after injection into it of platelet-rich or physiological saline of sodium chloride of autogenous plasma of not more than 40 ml with further providing physical activity of the joint in the aerobic load mode for 30–40 minutes. Two-component preparation is prepared by injecting thrombocyte-rich autoplasma or normal saline into a healthy knee that is followed by providing joint physical activity in an aerobic load mode for 30–40 min. Two-component preparation of platelet-rich synovial fluid or containing natural normal saline in amount of 25–40 ml is sampled from an articular cavity of a healthy joint.

EFFECT: group of inventions enables preparing the two-component preparation of the synovial fluid eliminating hyaluronic acid intolerance and providing the faster recovery of the injured joint tissues ensured by renewed composition of the synovial fluid at the early stage of treatment.

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