METABOLITES OF ALPHA-HYDROXYLATED FATTY ACIDS, MEDICAL APPLICATIONS AND USE THEREOF AS BIOMARKERS Russian patent published in 2025 - IPC C07C59/40 C07C59/42 C07C57/03 C07C69/533 C07C69/52 A61K31/201 A61K31/202 A61K31/231 A61K31/232 A61P35/00 A61P9/00 A61P25/00 

Abstract RU 2841595 C1

FIELD: chemistry.

SUBSTANCE: present invention relates to a sodium salt selected from the sodium salt of a compound of formula COOH-(CH2)a-(CH=CH-CH2)b-(CH2)c-CH3 (II), where: a=6, b=1 and c=6; a=6, b=2 and c=3; a=6, b=3 and c=0; a=3, b=3 and c=3; a=2, b=4 and c=3; and a=2, b=5 and c=0; and a sodium salt of a compound of formula COOH-(CH2)a-(CH=CH-CH2)m-(CH2)3-(CH=CH-CH2)(b-1-m)-(CH2)c-CH3, where a=1, b=6, c=0, and m=0. Disclosed compounds can be used to treat a disease or pathology associated with a change in the lipid composition of cell membranes, selected from the group consisting of neurological or neurodegenerative disease, cancer, neoplasm and neuropathic pain.

EFFECT: providing therapeutically active compounds (metabolites) which are obtained from other compounds or prodrugs, so that administration of such metabolites, separately, by means of their prodrugs or in combination with their corresponding prodrugs, modulation of the therapeutic effect and possible adverse side effects, depending on the patient's condition and the pathological condition to be treated.

14 cl, 24 dwg, 6 tbl, 7 ex

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RU 2 841 595 C1

Authors

Eskriba Ruis, Pablo Visente

Torres Kanalekho, Manuel

Buskets Ksaubet, Khaver

Llado Kanelyas, Viktoriya

Fernandes Garsiya, Paula

Rosselo Kastilo, Katalina Ana

Parets Barrios, Sebastiya

Beteta Gobel, Roberto

Kano Urrego, Emilse

Arbona Gonsales, Laura

Rodriges Lorka, Rakel

Kabot Bausa, Khuan

Milyares Pisa, Mark

Dates

2025-06-10Published

2021-01-28Filed