METABOLITES OF ALPHA-HYDROXYLATED FATTY ACIDS, MEDICAL APPLICATIONS AND USE THEREOF AS BIOMARKERS Russian patent published in 2025 - IPC C07C59/40 C07C59/42 C07C57/03 C07C69/533 C07C69/52 A61K31/201 A61K31/202 A61K31/231 A61K31/232 A61P35/00 A61P9/00 A61P25/00 

FIELD: chemistry.

SUBSTANCE: present invention relates to a sodium salt selected from the sodium salt of a compound of formula COOH-(CH₂)_a-(CH=CH-CH₂)_b-(CH₂)_c-CH₃ (II), where: a=6, b=1 and c=6; a=6, b=2 and c=3; a=6, b=3 and c=0; a=3, b=3 and c=3; a=2, b=4 and c=3; and a=2, b=5 and c=0; and a sodium salt of a compound of formula COOH-(CH₂)_a-(CH=CH-CH₂)_m-(CH₂)₃-(CH=CH-CH₂)_(b-1-m)-(CH₂)_c-CH₃, where a=1, b=6, c=0, and m=0. Disclosed compounds can be used to treat a disease or pathology associated with a change in the lipid composition of cell membranes, selected from the group consisting of neurological or neurodegenerative disease, cancer, neoplasm and neuropathic pain.

EFFECT: providing therapeutically active compounds (metabolites) which are obtained from other compounds or prodrugs, so that administration of such metabolites, separately, by means of their prodrugs or in combination with their corresponding prodrugs, modulation of the therapeutic effect and possible adverse side effects, depending on the patient's condition and the pathological condition to be treated.

14 cl, 24 dwg, 6 tbl, 7 ex