DOCOSAHEXAENOIC ACID DERIVATIVES AND THEIR APPLICATION AS DRUGS Russian patent published in 2012 - IPC C11C3/00 C07C227/04 C07C229/36 C07C231/02 C07C233/09 C07C317/44 C07C319/14 C07C323/54 C07C67/307 C07C67/31 C07C67/333 C07C69/587 C07C69/618 C07C69/65 C07C69/73 C07C69/734 A61K31/16 A61K31/232 A61P25/28 A61P3/04 A61P3/10 A61P9/10 

Abstract RU 2441061 C2

FIELD: medicine.

SUBSTANCE: invention refers to new compounds of formula (I) where X is carboxylic acid, carboxylates, carboxylic anhydride, diglyceride, triglyceride, phospholipid, or carboxamides, or to any their pharmaceutically acceptable salt. The invention particularly refers to (4Z, 7Z, 10Z, 13Z, 16Z, 19Z)-ethyl 2-ethyldocosa-4,7,10,13,16,19-hexanoate. The invention also refers to a food lipid composition and to a composition for diabetes, for reducing insulin, blood glucose, plasma triglyceride, for dislipidemia, for reducing blood cholesterol, body weight and for peripheral insulin resistance, including such compounds. Besides, the invention refers to methods for treating and/or preventing diabetes, dislipidemia, peripheral insulin resistance, body weight reduction and/or weight gain prevention, insulin, blood cholesterol, blood glucose and/or plasma triglyceride reduction.

EFFECT: higher clinical effectiveness.

61 cl, 4 tbl, 16 dwg, 5 ex

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RU 2 441 061 C2

Authors

Brin Morten

Kholmejd Ehnn Kristen

Kopetski Jan

Dates

2012-01-27Published

2006-05-04Filed