APPLICATION OF 2-HYDROXYDERIVATIVES OF POLYUNSATURATED FATTY ACIDS AS MEDICATIONS Russian patent published in 2014 - IPC C07C59/42 C07C59/60 C07C57/03 C07C57/12 A61K31/20 A61K31/231 A61K31/232 A61P25/00 A61P29/00 A61P3/00 A61P3/04 A61P35/00 A61P9/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medication for treatment or prevention of disease, which developed on the basis of structural and/or functional, and/or compositional changes of lipids in cell membranes, selected from cancer, vascular diseases, inflammatory diseases, metabolic diseases, obesity and excessive body weight, neurological or neurodegenerative disorders, which represents compound of formula COOR₁-CHR₂-(CH₂)_a-(CH=CH-CH₂)_b-(CH₂)_c-CH₃ (I) or its pharmaceutically acceptable salts and derivatives, selected from esters, ethers, alkyl, acyl, phosphate, sulfate, ethyl, methyl or propyl; in which a and c can have independent values from 0 to 7; b can have independent values from 2 to 7, where R₁ is selected from the following radicals: H, Na, K, CH₃O, CH₃-CH₂O and OPO(O-CH₂-CH₃)₂, and R₂ is selected from the following radicals: OH, OCH₃, O-CH₃COOH, CH₃, Cl, CH₂OH, OPO(O-CH₂-CH₃)₂, NOH, F, HCOO and N(OCH₂CH₃)₂.Invention also relates to application of formula (I) compound and pharmaceutical composition, which contains it.

EFFECT: medications, based on claimed compound, are more efficient than medications of preceding level of technology.

22 cl, 7 dwg, 16 tbl, 10 ex