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1 098 229

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(21) (22)

Application

3378381/04, 1982-01-08

(22)

Actual filing date

1982-01-08

(45)

Published

1998-02-20

(72)

Inventor

Artemov V.N.Vasil'Ev Ju.A.Konovkin A.I.Korotkikh N.I.Kucherjavenko V.I.Murashov B.A.Nosovskaja N.V.Shvajka O.P.

METHOD OF SYNTHESIS OF 1,4-DIGLYCIDYL-3-METHYL-1,2,4-TRIAZOLONE-5 Russian patent published in 1998 - IPC

Abstract SU 1098229 A1

FIELD: organic chemistry, chemical technology. SUBSTANCE: method involves acetylation of semicarbazide with acetic anhydride, cyclization of 1-acetylsemicarbazide in alkaline medium at heating, condensation of 3-methyl-1,2,4-triazolone-5 with epichlorohydrin at 98-100 C in the presence of lower tetraalkylhalogenides, dehydrochlorination of condensation products with alkali hydroxides at 50-52 C. Urea used as parent raw is hydrazinized at reaction mixture boiling for 1.5-2 h at inert gas bubbling, mainly nitrogen. Acetylation of semicarbazide is carried out at 70-80 C in atmosphere of inert gas, mainly nitrogen; cyclization of 1-acetylsemicarbazide is carried out at 98-100 C for 1-1.5 h, and condensation of 3-methyl-1,2,4-triazolone-5 with epichlorohydrin and dehydrochlorination of condensation product - in the presence of 20-30% water of triazolone mass. EFFECT: improved method of synthesis.

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SU 1 098 229 A1

Authors

Artemov V.N.

Vasil'Ev Ju.A.

Konovkin A.I.

Korotkikh N.I.

Kucherjavenko V.I.

Murashov B.A.

Nosovskaja N.V.

Shvajka O.P.

Dates

1998-02-20—Published

1982-01-08—Filed